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Based upon Marvel Comics’ most unconventional anti-hero, DEADPOOL tells the origin story of former Special Forces operative turned mercenary Wade Wilson, who after being subjected to a rogue experiment that leaves him with accelerated healing powers, adopts the alter ego Deadpool. Armed with his new abilities and a dark, twisted sense of humor, Deadpool hunts down the man who nearly destroyed his life.
- Ryan Reynolds as Wade Wilson/Deadpool
- Morena Baccarin as Vanessa Carlysle
- Ed Skrein as Francis Freeman/Ajax
- T.J. Miller as Jack Hammer/Weasel
- Gina Carano as Angel Dust
- Brianna Hildebrand as Negasonic Teenage Warhead
- Andre Tricoteux as Peter Rasputin/Colossus
- Stefan Kapicic as Peter Rasputin/Colossus (voice)
- Leslie Uggams as Blind Al
- Jed Rees as The Recruiter
- Karan Soni as Dopinder