Remus is the twin sister of Romulus, and used to help her brother with his mission to gain as much power as possible. That was until Romulus Sabretooth Wolverine, and herself broke into the Weapon X facility and Wolverine volunteered for the Adamantium bonding process. She told her brother to stop or she'd walk away from everything they had done. He wouldn't stop so she left. Romulus then had Professor Thorton erase Wolverine's memories particularly the ones that involved Remus.
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